Medicina, Free Full-Text
Background and Objectives: Orthostatic intolerance (OI) is a clinical condition in which symptoms worsen upon assuming and maintaining upright posture and are ameliorated by recumbency. OI has a high prevalence in patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Limited data are available to guide the treatment of OI in ME/CFS patients. We and others have previously described patient-reported subjective improvement in symptoms using compression stockings. We hypothesized that these subjective reports would be accompanied by objective hemodynamic improvements. Materials and Methods: We performed a randomized crossover trial in 16 ME/CFS patients. Each underwent two 15-min head-up tilt table tests, one with and one without wearing knee-high compression stockings that provided 20–25 mm Hg compression. The order of the tests was randomized. We measured heart rate and blood pressure as well as cardiac output and cerebral blood flow (CBF) using extracranial Doppler of the internal carotid and vertebral arteries. Results: There were no differences in supine measurements between the 2 baseline measurements. There were no differences in heart rate and blood pressure at either end-tilt testing period. Compared to the test with the stockings off, the mean percentage reduction in cardiac output during the test with compression stockings on was lower, 15 (4)% versus 27 (6)% (p < 0.0001), as was the mean percentage CBF reduction, 14 (4)% versus 25 (5)% (p < 0.0001). Conclusion: In ME/CFS patients with orthostatic intolerance symptoms, cardiac output and CBF are significantly reduced during a tilt test. These abnormalities were present without demonstrable heart rate and blood pressure changes and were ameliorated by the use of compression stockings.
Sample Resume of Internal Medicine Specialist with Template & Writing Guide
Medicina, Free Full-Text, tibia rings
Medicina, Free Full-Text
Medicina, Free Full-Text
IJERPH Free Full-Text Challenges In Preventive Practices
Medicina, Free Full-Text
PDF Online OST: Clinical Medicine for the MRCP PACES: Volume 1: Core Clinical Skills (Oxford Special by homatransouc - Issuu
Evidence-free medicine
PDF] Use of the Systematized Nomenclature of Medicine Clinical Terms (SNOMED CT) for Processing Free Text in Health Care: Systematic Scoping Review
Oxidative stress. From normal cells, to oxidative stress and aggressive free radicals, to cell death.Educational and study content for students of biology, medicine and science. vector illustration. 27117760 Vector Art at Vecteezy
Sports Activity After Surgical Treatment of Intra-articular Tibial, bäumlein 108 led
pub.mdpi-res.com/img/journals/medicina-logo-social
