PDF] Clinicopathologic Characteristics and Causes of
Atrophic endometrium was the most common cause of PMB in both groups, and approximately 12% of cases were associated with gynecological malignancy in older patients. Background This study aimed to reveal the clinicopathologic features and causes of bleeding in older patients with postmenopausal bleeding (PMB) and to investigate the correlation between the ultrasonographic findings and etiology of PMB. Methods We retrospectively analyzed the causes and clinical characteristics of PMB in 498 patients who were diagnosed between January 2007 and December 2017. The population with PMB was divided into 2 groups according to age: Group A (n=204) included individuals more than 65 years of age and group B (n=294) included those less than 65 years of age. Clinical characteristics such as age, parity, underlying conditions, previous surgical history, and previous menopausal hormone therapy were compared between the groups. Cervical cytology testing and transvaginal ultrasonography were performed in all patients with PMB. Endometrial biopsy was performed in all cases of endometrial thickness ≥5 mm. Results We examined 498 patients with PMB. In group A, atrophic endometrium (n=125, 61.27%) was the most common cause of PMB. Twenty-three patients had gynecological malignancy (cervical cancer: n=12, 5.88%; endometrial cancer: n=8, 3.42%; ovarian cancer: n=3, 1.46%), and 30 patients had benign gynecological disease (endometrial polyp: n=10, 4.90%; submucosal myoma: n=6, 2.94%; uterine prolapse: n=7, 3.42%; cervical dysplasia; n=5, 2.45%; cervical polyp: n=2, 0.98%). Forty patients had endometrial thickness ≥5 mm. Eight patients were diagnosed with endometrial cancer. All cases of endometrial cancer were diagnosed with endometrial thickness >10 mm. Conclusion Atrophic endometrium was the most common cause of PMB in both groups, and approximately 12% of cases were associated with gynecological malignancy in older patients.
PDF) Lymphocytic Gastritis: Clinicopathologic Features, Etiologic Associations, and Pathogenesis
PDF) Clinicopathologic Characteristics and Causes of Postmenopausal Bleeding in Older Patients
Animals, Free Full-Text
A multi-institutional observational study evaluating the incidence and the clinicopathological characteristics of NeoRAS wild-type metastatic colorectal cancer - ScienceDirect
PDF) Histopathologic characteristics of scleromyxedema: A study of a series of 34 cases
Comparative Clinicopathologic and Genomic Analysis of Hepatocellular Neoplasm, Not Otherwise Specified, and Hepatoblastoma - Modern Pathology
Development and validation of postoperative circulating tumor DNA combined with clinicopathological risk factors for recurrence prediction in patients with stage I-III colorectal cancer, Journal of Translational Medicine
PDF] Clinicopathologic Characteristics and Causes of Postmenopausal Bleeding in Older Patients
Clinicopathological characteristics, risk factors and renal outcome in IgA nephropathy with crescents
Clinicopathologic and genomic features of lobular like invasive mammary carcinoma: is it a distinct entity?
PDF) Clinicopathological Study of Eosinophilic Cholecystitis: Five Year Single Institution Experience
PDF) Clinicopathologic Characteristics and Causes of Postmenopausal Bleeding in Older Patients
Clinicopathological characteristics and outcomes of lupus nephritis patients with scanty immune depositions in kidney biopsies
Clinicopathological characteristics of solitary cavitary lung cancer: a case-control study - Liu - Journal of Thoracic Disease
Molecular profiling obtains information of clinicopathological features of meningioma - Trepo
